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Musculoskeletal biomechanics: articles, publications, and clinical model

Mauro Lastrico, Laura Manni – Physiotherapists

The AIFIMM biomechanical model is an analytical and systemic clinical framework for interpreting pain, dysfunction, and joint and spinal pathologies. This page collects its theoretical foundations, clinical applications, and international publications. Each article is available as a downloadable PDF, complete with figures and references.

Theoretical foundations of the model Articles defining the physical and biomechanical principles.

Muscle Connective Tissue Shortening: An Integrated Biomechanical Model of Joint Degeneration – indexed article

How muscle shortening generates joint conflict: the role of connective tissue

Do antigravity muscles really oppose gravity?

Why joint conflict develops: vector analysis of muscular forces

Segmental analysis Vector analysis of the main joint and spinal regions.

Cervical hyperlordosis, straightening, and forward head: biomechanical causes and disc compressions

Thoracic kyphosis, lumbar lordosis, and spinal straightening: vector analysis in the sagittal plane

The hyoid bone in cranio-cervical biomechanics: a point of mechanical convergence and force redistribution

Vertebral rotation and radicular compression: vector analysis in the frontal and rotatory plane

Scoliosis: vertebral rotation, lateral deviation, and biomechanical intervention criteria

Cranio-cervico-mandibular disorders: when jaw pain comes from the neck and vice versa

Shoulder, elbow, and epicondylitis: vector analysis of the upper limb

Knee and hip: valgus, varus, hyperextension, and intra-articular compressions

Flat foot, cavus foot, and hallux valgus: vector analysis of the medial arch, anterior arch, and hallux

Systemic model and clinical reasoning How the system organises, why symptoms develop, how to assess, and how to intervene.

Beyond muscle chains: the musculoskeletal system as a complex system

Pain neuroscience and muscle shortening: three systems, one final effector

Why the symptom returns: clinical reasoning in musculoskeletal pain diagnosis

Why muscle strengthening alone does not correct joint alignment

 

Books

Musculoskeletal Biomechanics and the Mézières Method- Mauro Lastrico — Demi Edizioni, Roma (1st ed. 2016, 3rd reprint 2023) Original theoretical foundation of the model.

Physics of the Musculoskeletal System — From the Vector Model to Clinical Reasoning - Mauro Lastrico, Laura Manni — forthcoming 2026 Advanced systematisation of the theoretical framework.

Articles published in indexed scientific journals

Lastrico M. An integrated biomechanical model linking connective tissue shortening, segmental load distribution, and vectorial dominance to predict joint degeneration patterns. Medical Hypotheses (Elsevier). 2026. DOI: https://doi.org/10.1016/j.mehy.2026.112052

Indexed on PubMed, Scopus, Web of Science.

Internationally published articles The following articles were submitted to independent editorial review and published by the CPD Certification Service (UK), with verification of theoretical consistency and integration of bibliographic sources.

Muscle Shortening and Joint Dysfunction – Physical and Clinical Mechanisms

Body Equilibrium – A Physical-Clinical Interpretation of Human Upright Stability

Vector Analysis in Musculoskeletal Biomechanics - Part 1: Foundations and Clinical Principles

Vector Analysis in Musculoskeletal Biomechanics - Part 2: Clinical Applications and Case Interpretation

Vector Analysis of the Vertebral Column in the Sagittal Plane - Clinical Application to Vertebral Equilibrium

The Hyoid Bone: Biomechanical Analysis of a Mechanical Convergence Point-Force Redistribution in the Cranio-Cervical District

Vector Analysis of the Vertebral Column in the Frontal Plane – Part 1

Vector Analysis of the Vertebral Column in the Frontal Plane – Part 2

TMJ Biomechanical Analysis - Part 1: Systemic Relationships, Hyoid Function and Dental Influence

TMJ Biomechanical Analysis - Part 2: Muscular Mechanisms, Joint Locking and Clinical Tests

Biomechanical Analysis of the Shoulder – Part 1: Vectorial Dominances in Scapular and Humeral Position

Biomechanical Analysis of the Shoulder – Part 2: Scapulohumeral Impigement, Subluxations and Therapeutic Implications

Biomechanical Analysis of the Lower Limb – Part 1: Vectorial Dominances of the Hip and Knee

Biomechanical Analysis of the Lower Limb – Part 2: Vectorial Dominances of the Foot

The Muscle as Final Effector: Three Converging Systems

From Muscular Chains to Complex Systems

Clinical Reasoning in Musculoskeletal Biomechanics - Part 1: The Four Constants and Differential Diagnosis

Clinical Reasoning in Musculoskeletal Biomechanics - Part 2: Primary and Secondary Shortenings and the Two Equations

AIFIMM Formation - Institute of Applied Musculoskeletal Biomechanics
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